FRI0053 Antibodies to a subset of citrullinated peptide antigens correlate with neutrophil extracellular trap levels in the sputum of subjects at-risk for future ra

BackgroundPrior data suggest that anti-citrullinated protein/peptide antibodies (ACPA) may originate in the lung prior to the onset of synovitis in rheumatoid arthritis (RA) (1). Neutrophil extracellular trap (NET) formation is one potential mechanism that could trigger or be associated with local A