23 METABOLIC-HORMONAL CHANGES IN INFANTIL OBESITY

We investigate if infantile obesity could associate to hyperinsulinism, insulin resistance, hyperandrogenism by ovarian hyperstimulation and decrease in the SHBG levels in serum, mediated by means of the IGF-I receptors. 29 obese and 9 normal girls underwent an oral glucose tolerance test with insulin dosage by RIA at 0-30-60 and 120 minutes, and:T3 and T4 by RIA, TSH, LH, FSH, PRL, IGF-I and SHBG by IRMA. a) Clinical characteristics of both groups (X±SD) b) Oral glucose tolerance test (X±SD) c) Other determinations Infantil obesity associated with hiperinsulinism could lead to hyperandrogenism.