P28 – 2664: Vagus nerve stimulation in the treatment of pharmacoresistant epilepsy in 29 children

Objective To evaluate the efectiveness of vagal stimulation in a population of children and adolescent with refractory epilepsy. Methods This is a monocentre, retrospective study, which studied the files of 29 children implanted between 1995 and 2012 with a vagus nerve stimulator. The rate of responders (reduction by more than 50% of the frequency of seizures), the antiepileptic efficacy according to the type of epilepsy or to the age of implantation or to the age of the start of epilepsy, the side effects, the overall quality of life and the number of hospitalisations were studied. Results VNS, for all types of epilepsy, brought a significant reduction of the frequency of seizures throughout the follow-up (p Conclusion The stimulation of the vagus nerve is a sure and effective therapeutic alternative that would be discussed for a child with refractory epilepsy when a surgical approach is not possible.