Overview of oral tolerance induction for prevention of food allergy - where are we now?

Oral tolerance induction through early introduction of allergenic food has proven effective in randomized controlled trials. This new approach to weaning has beenincorporated into many national and international infants' feeding guidelines. However, there are questions thatrequire further discussion, such as, which foods should be introduced early, should the intervention be targeted to infants at high risk or to the general population, and what is the ideal timing for early food introduction. This review examines the extent to which recent trials address these critical questions and highlights areas where further research is required.