PATIENTS WITH GENOTYPE-POSITIVE HYPERTROPHIC CARDIOMYOPATHY ARE AT INCREASED RISK OF HEART FAILURE RELATED DEATH

Pathogenic sarcomere mutations are found in about 50% of hypertrophic cardiomyopathy (HCM) patients. Currently, clear genotype-phenotype relations are lacking. This study compares phenotype and outcome in genotype positive (G+) and genotype negative (G-) HCM. Between January 2004 and 2012, 431 HCM