The Role of Biomechanics in Analysis of Cardiovascular Diseases: Regulation of the Fluid Shear Response by Inflammatory Mediators

Biomechanics at the level of individual cells, the microcirculation and the tissue is an effective tool to analyze important diseases such as stroke, myocardial infarction, or physiological shock. The biomechanics of inflammation needs to take center stage in the analysis of disease, organ rejection, or tissue engineering. There is a rich collection of problems that require analysis and finding solutions will be a rewarding exercise. The role of fluid shear stress in control of cells in the cardiovascular system is a major aspect of these problems.