Abstract WMP63: Neuroimaging Findings and Incidence of Atrial Fibrillation on Follow-up in Patients With Embolic Stroke of Undetermined Source

Background and purpose: paroxysmal AF is detected during follow-up in approximately 30% of ESUS. We aim to identify patterns of brain lesions suggestive of embolic events and to evaluate the incidence of AF during 4-years of follow-up. Design and method: acute ischemic stroke patients were prospectively included in a multidisciplinary secondary stroke prevention program. Cardioembolic stroke was ruled out with 12-lead ECG, 48-hour cardiac monitoring and transesophageal echocardiography. Large artery disease of intracranial and extracranial vessels was evaluated with MR or CT angiography or cervical duplex plus transcranial doppler ultrasonography. After this thorough evaluation, patients without cardioembolic or large artery disease and non-lacunar lesion on MRI were defined as ESUS. Results: 479 (34%) of 1376 ischemic strokes included from September 2009 to December 2016 were ESUS; median age 78 years (IQR 69-84), 55% female. Pre-stroke VRF profile: 80% HT, 66% dyslipidemia, 14% DM, 51% obesity, 39% smok...