Surgery for Type A Aortic Dissection: 14-year Contemporary Cohort Study

2020 
Background Type A aortic dissection is a fatal condition warranting emergency surgery to prevent complications and death. We reviewed the contemporary trends, characteristics, outcomes and predictors of this operation at our centre over a 14-year period. Methods Consecutive patients undergoing type A aortic dissection surgery at Auckland City Hospital during March 2003–March 2017 were studied, and relevant characteristics and outcomes collected prospectively for statistical analyses. Results There were 327 patients included, and the number of operations each year remained similar from 2003–2010, and steadily increased thereafter. Median age was 60.6 years, with 124 (37.9%) females, 136 (41.6%) Maori or Pacific ethnicity, 319 (97.6%) emergency surgeries, 62 (19.0%) in a critical preoperative state and 154 (47.1%) having a malperfusion syndrome. Operative mortality occurred in 65 (19.9%), although this has decreased from 23.3% before 2014 to 14.0% since. Composite morbidity occurred in 212 (65.0%), predominantly acute kidney injury 134 (41.0%), ventilation >24 hours (129 (39.6%), return to theatre 94 (28.8%) and stroke 63 (19.3%). Survival at 1, 5 and 10 years was 79.0%, 71.7% and 57.8% respectively. Critical preoperative state and malperfusion syndrome were independent predictors of operative and long-term mortality and composite morbidity. Conclusion Surgery for acute type A aortic dissection has been increasing since 2011 and continues to have high rates of operative mortality and morbidities, although the former has decreased since 2014. Critical preoperative state and malperfusion were the key predictors of adverse outcomes. After surviving the perioperative period, prognosis was good with low rates of late mortality.
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