Abstract W P290: Left Ventricular Diastolic Dysfunction Deters Functional Recovery After Acute Ischemic Stroke

Background: Diastolic dysfunction of left ventricle (LV) is associated with heart failure symptoms and restricts exercise capacity even in patients with preserved LV ejection fraction. LV diastolic dysfunction is readily evaluated by the conventional Doppler echocardiography. We hypothesized that LV dysfunction may deter functional recovery and increase vascular events in acute ischemic stroke patients. Methods: From a total of 4808 patients who admitted to a tertiary academic hospital between August 2007 and June 2013, we selected image-documented cases (N=3858) and subjects with echocardiographic evaluation within 1 month before or after the index stroke (N=3175; 66% of the eligible population). We excluded cases without adequate echocardiographic data for evaluation of LV diastolic dysfunction (N=213) and mRS score at 3 months (N=17). LV diastolic dysfunction was graded into 4 groups in accordance with the current guideline: normal (including restricted patterns), grade 1, grade 2 and grade 3 dysfuncti...