Abstract 19603: Disruption of βPDGF Receptor-Dependent PI3k and Plcγ Signaling Protects from Hypoxia-Induced Pulmonary Hypertension

Henrik ten Freyhaus,Wiebke Janssen,Maike Leuchs,M. Zierden,E. M. Berghausen,Marius Vantler,Evren Caglayan,Ralph T. Schermuly,Michelle D. Tallquist,Stephan Rosenkranz

Abstract 19603: Disruption of βPDGF Receptor-Dependent PI3k and Plcγ Signaling Protects from Hypoxia-Induced Pulmonary Hypertension

2012

Henrik ten Freyhaus
Wiebke Janssen
Maike Leuchs
M. Zierden
E. M. Berghausen
Marius Vantler
Evren Caglayan
Ralph T. Schermuly
Michelle D. Tallquist
Stephan Rosenkranz

Background: Vascular remodeling is critical during the pathogenesis of pulmonary hypertension (PH). Growth factors, such as platelet-derived growth factor (PDGF), appear to be involved in these pro...

Keywords:

Pulmonary hypertension
Pathogenesis
Hypoxia (medical)
PI3K/AKT/mTOR pathway
Endocrinology
Diabetes mellitus
Growth factor
Cardiology
Receptor
Internal medicine
Medicine
Platelet-derived growth factor receptor

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