HIGH FUROSEMIDE DOSE IS AN INDEPENDENT RISK FACTOR FOR MORTALITY IN PATIENTS WITH CHRONIC HEART FAILURE

2012 
Diuretics relieve congestion in HF patients but activate the renin-angiotensin-aldosterone system (RAAS). High furosemide doses have been correlated with higher mortality; it is not clear whether higher diuretic doses represent a marker of disease severity or an independent prognostic factor. We
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