Clinical features and outcome in females and males with ruptured intracranial saccular aneurysms

Of 1076 patients with aneurysmal subarachnoid haemorrhage 674 were females and 402 males. No significant differences between females and males were seen as regards age, clinical condition on admission, pre-existing arterial hypertension and number of rebleeds. Angiographically demonstrated vasospasm was seen with a significantly higher incidence in females (p<0.05) which may possibly explain a significantly poorer outcome in females compared with males (p<0.05), despite the much higher rate in females of internal carotid artery aneurysms which have a significantly better prognosis compared with aneurysms at other sites.