Perinatal asfiksili yenidoğanlarda elektroensefalorgrafi bulgularının ve seyrinin değerlendirilmesi Orijinal Araştırma

Aim: This study was perormed to assess the predictive value of standard electroencephalogram EEG in full term infants with hypoxic ischaemic encephalopathy Material and Method: This prospective study consisted of 31 full term 37 42 weeks of gestation newborns with perinatal asphyxia electroencephogram EEG was recorded as soon as possible in the first 48 hours of life The recordings were divided into four categories 1 normal or slightly abnormal 2 intermediate 3 very abnormal and 4 extremely abnormal EEGs In addition neonates were classified in three grades as having mild moderate and severe hypoxic ischemic encephalopathy using Amiel Tison clinical criteria according to Sarnat and Sarnat classaficitaion Results: In our study the unfavorable outcome rate was 35 5 n=11 Three infants with extremely abnormal EEGs group IV and havingsevere hypoxic encephalopathy gradeIII died Among 14 infants with very abnormal EEGs group III four died all of four had clinically severe hypoxic ischemic encephalopathy grade III two had sequelae they had moderate hypoxic ischemic encephalopathy grade II Two infants with intermediate activity group II and having moderate phypoxic ischemic encephalopathy grade II had also squeal Newborns with normal or slightly abnormal EEGs group I and having mild hypoxic ischemic encephalopathy grade I had no unfavorable outcome nbsp; sequelae or death There was a highly significant relationship between unfavorable outcome and hypoxic ischameic encephalopathy grades or EEG findings r=0 65; P lt;0 0001 EEG had an excellent sensitivitry rate 90 5 and specificity rate 80 Infants with intermediate EEG activity had a 25 times higher risk of unfavorable outcome compared to infants with a normal EEG This risk was 54 times higher for infants with nbsp; an extremely abnormal EEG Conclusions: In conclusion EEG has an important predictive value in asphyxiated newborns and it has a great early sensitivity and specificity Key words: Perinatal asphyxia prognoz standart EEG