Abstract 100: In-Hospital Delirium and Long-Term Cognitive Outcomes Among Patients With Ischemic Stroke: A Population-Based Cohort Analysis

Introduction: Evidence of association between delirium during initial hospitalization of ischemic stroke (IS) patients, and development of long-term mild cognitive impairment or dementia (MCID) is lacking. We examined the prospective incident risk of MCID among IS patients who experienced in-hospital delirium in a large multi-state population-based cohort. Methods: We utilized NY, CA, and FL (2005 - 2014) State Inpatient and Emergency Department Databases, and established a cohort by selecting MCID free patients with a primary diagnosis of IS (ICD-9: 433.x1, 434.x1, 436) during a 2yr period. Delirium during the initial IS event was tagged using a validated algorithm with high specificity for the confusion assessment method. The cohort was followed for MCID diagnoses. Patients that died within 90 days of initial IS event were excluded. We conducted time-to-event analyses and report cumulative incidence, 95% Confidence Interval (CI) and hazard ratios (HR) for risk of MCID among IS patients with and without ...