Abstract 103: Infarct Patterns in the Anterior Circulation as Predictors of Recurrent Stroke in the Medical Arm of SAMMPRIS

Introduction: A previous SAMMPRIS analysis showed that stroke as the qualifying event and old infarct in the territory of the stenosis were independently associated with recurrent stroke in the medical arm. We sought to refine these findings by characterizing the relationships between the patterns of infarcts on baseline brain imaging, collateral flow, and risk of stroke. Methods: In the medical arm of SAMMPRIS, 101 patients had acute infarcts in the territory of a stenotic MCA or ICA stenosis on baseline imaging. Blinded to patient outcome, infarcts were characterized as involving primarily the core MCA, internal or cortical borderzone (BZN), or perforator territories. Among these 3 subgroups, the time to primary endpoint (logrank test) and collateral blood flow on baseline angiography (Chi-square tests) were compared. Old infarcts in the same territory were also characterized according to infarct patterns and correlated with acute infarct patterns and outcome. Results: The table shows rates of stroke in...