Familial autoimmune myasthenia gravis
1994
We describe a family with parental consanguinity and five of 10 siblings affected by late-onset autoimmune myasthenia gravis. We propose a genetic mechanism as a predisposing factor in this family. Our analysis excludes the major histocompatibility complex, the β subunit of the acetylcholine receptor, and the T-cell receptor α and β subunits as candidate genes for the disorder in this family.
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