Lycopene supplementation reduces TNF-α via RAGE in the kidney of obese rats

D. T. Pierine,M. E. L. Navarro,I. O. Minatel,Renata de Azevedo Melo Luvizotto,Andre F. Nascimento,Ana Lúcia dos Anjos Ferreira,Kyung-Jin Yeum,Camila Renata Corrêa

Lycopene supplementation reduces TNF-α via RAGE in the kidney of obese rats

2014

D. T. Pierine
M. E. L. Navarro
I. O. Minatel
Renata de Azevedo Melo Luvizotto
Andre F. Nascimento
Ana Lúcia dos Anjos Ferreira
Kyung-Jin Yeum
Camila Renata Corrêa

Background: The kidney is a target organ for injuries caused by advanced glycation end products (AGEs) in obesity. The receptor of AGEs (RAGE) is proinflammatory and appears to have a role in the pathogenesis of renal disease due to obesity.

Keywords:

Obesity
Proinflammatory cytokine
Glycation
Pathogenesis
Tumor necrosis factor alpha
Disease
Endocrinology
Kidney
Internal medicine
Medicine
Diabetes mellitus
Receptor

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