Guiding HIV therapy according to immunological status - the experience of virological knowledge.

Human Immunodeficiency Virus (HIV) was first related with Acquired Immunodeficiency Syndrome (AIDS) in 1983, and since then many attempts have been made to treat, control and in the last couple of years several studies have been conducted with the intention of achieve a cure or at least a functional cure. The understanding of the replication of the virus, has lead a new course of investigation regarding the best treatment options defined with, when to treat and how to treat to achieve the better response regarding the full and fast recover of the patient’s immune response. In this regard several strategies have been presented and discussed through the years, like the initial treatment for one side and the maintenance treatment for other side. The authors present a review of the state of the art and the perspective of treatments according the steps of the replication of the virus reflected in the immunological status of the patient.