AB1283 The prevalence and comorbidities associated with psoriatic arthritis in patients with psoriasis: an observational cohort study

Background The prevalence and comorbidities of psoriatic arthritis (PsA) varies in different parts of the world and there is little clinical and epidemiological data from the Egyptian Objectives: To investigate the prevaalence of psoriatic arthritis (PsA) in patients with psoriasis (PsO), and to identify comorbidities associated with it. Methods: The study was designed as a observational cohort study involving patients with psoriasis. Information was collected about lifestyle, habits, comorbidities, and psoriasis activity. Patients were classified as having PsA if they fulfilled the criteria of the Classification of Psoriatic Arthritis Study group (CASPAR). Results: The data was obtained from the 371 psoriasis patients. The mean age was 40.0±16.6 years, 42% were women, and 58% were men. A diagnosis of PsA was found in 104 patients (28%), of whom 34.6% had peripheral involvement, 15.4% had isolated axial involvement, and 50% had both peripheral and axial involvement. The PsA onset was preceding psoriasis in 48%, together with psoriasis in 40% and following psoriasis in 12%. Family history of PsO and PsA was positive in 21.6% and 8.4% respectively. PASI score of our patients ranged from 1–30 with a mean of 8.77±6.33, which were relatively higher in PsA patients. Comorbidities in form of diabetes mellitus, hypertension, liver disease, HIV and dyslipidemia were found in 14.6%, 10.5%, 10.2%, 0.3% and 0.5% respectively. Smoking was found in only10 patients (2.7%). Conclusions: The prevalence of PsA in Egyptian patients with psoriasis appears to be within the range reported in other studies. Whereas, most of PsA onset was found to precede the psoriasis. Disclosure of Interest None declared