A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

Brian Finan,Bin Yang,Nickki Ottaway,David L. Smiley,Tao Ma,Christoffer Clemmensen,Joe Chabenne,Lianshan Zhang,Kirk M. Habegger,Katrin Fischer,Jonathan E. Campbell,Darleen A. Sandoval,Randy J. Seeley,Konrad Bleicher,Sabine Uhles,William Riboulet,Jürgen Funk,Cornelia Hertel,Sara Belli,Elena Sebokova,Karin Conde Knape,Anish Konkar,Daniel J. Drucker,Vasily Gelfanov,Paul T. Pfluger,Timo D. Müller,Diego Perez-Tilve,Richard D. Dimarchi,Matthias H. Tschöp

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

2015

A rationally designed peptide agonist that targets three key hormone receptors reduces obesity and its complications in a manner superior to other agonists.

Keywords:

Obesity
Immunology
Agonist
Hormone receptor
Medicine
Diabetes mellitus
Peptide

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