The Relationship between Body Composition Analysis, Erythropoietin Requirements and Hemoglobin Variability in Hemodialysis Patients Hemodiyaliz Hastalarinda Hemoglobin Stabilitesi, Eritropoetin İhtiyaci ve Vücut Kompozisyon Analizi İlişkisi

OBJEctIVE:�Despiteofsimilarbodyweightandbodymassindexpatientsmighthavedifferentbody� composition.�OuraimwastoanalyzetherelationshipbetweenHbvariability,�rHuEPOrequirements� andbodycompositionanalysisofMHDpatients.� MAtErIAL and MEtHOdS:� MonthlylaboratoryvaluesandrHuEPOrequirementsof�110�MHD� patientswerecollected.�PatientsweregroupedaccordingtoHbvariabilityduringlast�6�monthsasGroup� LS�(lowstable,�Hb<10�g/dL,�n:�24),�GroupHS�(highstable,�Hb≥10�g/dL,�n:43),�GroupV�(variable,�Hb� varyingbetweentarget,�lowtargetandhightargetlevels,�n:43).� rESuL tS:�GroupLShadhigherCRPbutloweralbuminlevelscomparedtoGroupHSwhileGroupV� patientshadloweralbumincomparedtoHSandlowerCRPlevelscomparedtoLSpatients�(p:�0.005).� GroupLSpatientsrequiredsignificantlyhigherrHuEPOcomparedtoothergroups�(p:0.0001).�Group� HSpatientshadsignificantlyhighermusclemass�(p:0.042)�andmuscleratio�(p:0.018)�comparedto� GroupLS.�� cONcLuSION: NotonlychronicinflammationbutalsonutritionalstatusiscloselyrelatedwithHb� variability.�Webelievethatthereisatendencytoloseallbodycomponentsincaseofmalnutrition� associatedwithchronicinflammationwhileinmalnutritionpatientswithoutchronicinflammationthere�