Tyramine conjugation deficit in patients with chronic idiopathic temporomandibular joint and orofacial pain.

Abstract This study was carried out to explore the value of the tyramine conjugation test, an established trait marker for ‘endogenous unipolar depression’, in patients with chronic idiopathic temporomandibular joint and orofacial pain. Our results show that the pain patients excrete significantly lower amounts of tyramine sulphate than controls ( P