Common and specific risk factors for ischemic stroke in elderly: Differences based on type of ischemic stroke and aging

Abstract Background The risk factors among the types of ischemic stroke (atherothrombotic cerebral infarction: ATI, cardio-embolic infarction: CEI, lacunar infarction: LI) in aged stroke patients have rarely been compared to each other. Methods We compared the clinical parameters of 300 elderly patients with ischemic stroke, age 65–98 years, to 100 age-matched control patients. Results Comparison by parametric test and logistic regression analysis between all 300 and 100 control patients showed higher systolic and diastolic blood pressures ( p p  = 0.03), lower estimated glomerular filtration rate (eGFR) ( p  = 0.01), larger cardiothoracic ratio (CTR) ( p p p n  = 100 for each) showed the highest atheromatous risk factors for ATI to be hemoglobin A1c ( p  = 0.01) and low-density lipoprotein ( p p p p  = 0.054). Comparison between those aged n  = 150 for each) showed a lower eGFR ( p  = 0.02) and larger right atrial dimension ( p Conclusion The risk factors were quite different among the subtypes and aging.