Case Series of Three Infants with Erythema Multiforme Following Hepatitis B Vaccination

Erythema multiforme (EM) is an acute, self-limited, sometimes recurring mucocutaneous condition characterized by distinctive target lesions, and it has been associated with infections, accounting for up to 90% of cases, as well as with drugs, and other triggers. Most cases of EM occur in children, adolescents, and young adults, but rarely occur in neonates and infants. Here, we report three infants in whom EM developed following hepatitis B vaccination.