Acute Cutaneous Drug Reaction- Bullous Pemphigoid: Case Report

Any drug is a potentially impending cause of adverse hypersensitivity reaction. Cutaneous adverse drug reactions are common, but these reactions generally have a late onset: from days to months after drug intake. Most common drugs that cause bullous pemphigoid are penicillamine, furosemide and penicillins. Cephalosporins are known as safe antibiotics and rarely lead to severe side effects. A case of, probably the first, rapid onset of acute cutaneous drug reaction after the first oral intake of a cephalosporin was presented here. This rare case report addresses the fact that severe cutaneous drug reactions can occur immediately after onset of oral cephalosporin therapy.