Population pharmacokinetics of mizoribine in pediatric patients with kidney disease.

Hisashi Kaneda,Masaki Shimizu,Kazuhide Ohta,Katsumi Ushijima,Yoshimitsu Gotoh,Kenichi Satomura,Takuhito Nagai,Mikiya Fujieda,Masashi Morooka,Takuji Yamada,Masayoshi Yamada,Naohiro Wada,Mari Takaai,Yukiya Hashimoto,Osamu Uemura

Population pharmacokinetics of mizoribine in pediatric patients with kidney disease.

2016

Hisashi Kaneda
Masaki Shimizu
Kazuhide Ohta
Katsumi Ushijima
Yoshimitsu Gotoh
Kenichi Satomura
Takuhito Nagai
Mikiya Fujieda
Masashi Morooka
Takuji Yamada
Masayoshi Yamada
Naohiro Wada
Mari Takaai
Yukiya Hashimoto
Osamu Uemura

Background The present study aimed to obtain information enabling optimisation of the clinical effect of mizoribine (MZR) in pediatric patients with kidney disease.

Keywords:

Diabetes mellitus
Drug Dosage Calculation
Endocrinology
Internal medicine
Mizoribine
Kidney disease
Population
Intensive care medicine
Pediatrics
Medicine
Pharmacokinetics
area under curve
population pharmacokinetics
intestinal absorption
biological availability

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