Effects of Aspirin (325 mg/day) on Serum High- Sensitivity C-Reactive Protein, Cytokines, and Adhesion Molecules in Healthy Volunteers

In this study of healthy middle-aged and elderly subjects, we found that self-reported family history of premature heart attack and sudden death is independently associated with reduced HRV, suggesting that autonomic imbalance may be part of the complex of familial predisposition to premature heart attack.