Progress of diagnosis and treatment of acute kidney injury after liver transplantation

Liver transplantation is currently the main method for treating end-stage liver disease, but acute kidney injury (AKI) often occurs after transplantation, which directly or indirectly affects the recipient′s quality of life and long-term survival after transplantation. The pathogenesis and pathologic changes of AKI after liver transplantation are complex and diverse. A variety of factors (including donor and recipient factors, the use of surgery and early immunosuppressive agents after transplantation and so on) may cause AKI before, during, and after transplantation. This article tries to review the research progress on liver transplantation recipients accompanied with AKI after transplantation. The pathogenesis, and clinical diagnosis and treatment experience for AKI after liver transplantation are summarized, with a view to providing a basis for clinical prevention and early diagnosis and treatment, and improving the prognosis of the recipients. Key words: Liver transplantation; Acute kidney injury; Risk factor; Immunosuppressor