Lactate quartile concentration and prognosis in severe sepsis and septic shock

The Surviving Sepsis Campaign (SSC) indicates that a lactate (LT) concentration greater than 4 mmol/l indicates early resuscitation bundles. However, several recent studies have suggested that LT values lower than 4 mmol/l may be a prognostic marker of adverse outcome. The aim of this study was to identify clinical and analytical prognostic parameters in severe sepsis (SS) or septic shock (ShS) according to quartiles of blood LT concentration.