Evaluation of HCMV and EBV in odontogenic cysts fluids by molecular biological methods

Introduction: Odontogenic cysts are commonly seen pathological lesions in the jaw bones. Odontogenic cysts may be inflammatory or developmental regarding their origin. Pathogenesis differs due to the types of the odontogenic cysts and recurrence may be observed. Including periapical lesions, the roles of oral bacteria on periodontal infections were stated, however a study conducting the identification of the bacteria was not found before. Along with this, viruses such as human cytomegalovirus and Epstein Barr virus were observed on the inflammatory cells present in the periodontal lesions. However the role of the virus presence in the odontogenic cysts’ ethiopathology was not stated. The main purpose of this study is to evaluate the role of the Human Cytomegalovirus (HCMV) and the Epstein–Barr (EBV) viruses in the pathogenesis of the radicular cysts’ (RCs) and odontogenickeratocysts’ (OKCs) fluids.