LEFT ATRIAL APPENDAGE CLOSURE IN PATIENTS WITH CONTRAINDICATIONS TO ORAL ANTICOAGULATION THERAPY: A SYSTEMATIC REVIEW AND POOLED META-ANALYSIS

Left atrial appendage closure (LAAC), as an alternative stroke prevention strategy, is currently limited mainly to non-valvular atrial fibrillation (AF) patients who are eligible for oral anticoagulation therapy (OAT). However, patients with contraindication to OAT are the biggest potential benefit