Abstract WP33: Impact of Treatment Time on the Long-term Outcome of Stroke Patients Treated With Mechanical Thrombectomy

Background: Mechanical thrombectomy is the standard of care for patients presenting with acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Recent studies have shown that door to reperfusion time is longer during nighttime and weekends. In this study we examine the long term functional outcome of stroke patient treated with mechanical thrombectomy performed during work hours (on-hours) versus after hours (off-hours). Methods: Data on all patients receiving mechanical thrombectomy at a comprehensive stroke center between Dec/2014 and Dec/2016 was collected. Our primary outcome was the 90-day Modified Rankin Scale (mRS). Independent variables included receiving thrombectomy during on-hours (7am and 4pm) or off-hours 4pm-7am, weekends, and official holidays), admission NIH stroke scale, age, race, and sex. Multivariable logistic regression was used to examine the relationship between off-hours thrombectomy and mRS, controlling for patient baseline characteristics. Chi-square and t-tests were us...