НАРУШЕНИЯ СНА И РИСК АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИИ И ИНСУЛЬТА В ОТКРЫТОЙ ПОПУЛЯЦИИ СРЕДИ ЖЕНЩИН 25-64 ЛЕТ В РОССИИ/СИБИРИ (ПОПУЛЯЦИОННОЕ ИССЛЕДОВАНИЕ — ПРОГРАММА ВОЗ “MONICA-PSYCHOSOCIAL”)

Aim . To assess the influence of sleep disorders (SD) on the risk of arterial hypertension (AH) and stroke during 16 years follow-up in open population of females 25-64 y.o. Material and methods . Under the framework of WHO program “MONICA-psychosocial” (Multinational Monitoring of Trends in cardiovascular disease — psychosocial study) in 1994, the random representative cohort was assessed, of women (n=870) at the age 25-64 y.o., living in the district of Novosibirsk city. SD were studied by Jenkins C.D. test. During 16-year follow-up (1994-2010) in the cohort, all new cases of AH/stroke were assessed. Cox-proportional regression was implemented for the development risk of AH/stroke. Results . The prevalence of SD in open female population of 25-64 y.o. was 5,3%. Risk of development of AH was 4,3 times and 2,7 times higher for the first 5 and 10 years of follow-up, respectively, in females with SD, comparing to normal sleep. Stroke development risk was 1,95 times in SD women comparing to normal sleep, for 16 years follow-up. Conclusion . Prevalence of SD in open female population 25-64 y.o. is significant, and impact the risk of AH/stroke onset in 16 years.