Abstract WMP29: Hemorrhage Associated With Ventriculoperitoneal Shunt Placement in Aneurysmal Subarachnoid Hemorrhage Patients on Dual Antiplatelet Therapy: A Retrospective Analysis

Object: Intracranial stenting and flow diversion requires the use of dual antiplatelet therapy (DAPT) to prevent in-stent thrombosis. DAPT may significantly increase the risk of hemorrhagic complications in patients who require subsequent surgical interventions. In this study, we sought to investigate whether DAPT is a risk factor for hemorrhagic complication associated with ventriculoperitoneal (VP) shunt placement in aneurysmal subarachnoid hemorrhage (aSAH) patients. Methods: Patients with aSAH who presented to our institution from July 2009 through November 2016 requiring VP shunt placement for persistent hydrocephalus were included. The rates of hemorrhagic complication associated with VP shunt placement were compared between patients who were on DAPT (Aspirin and Clopidogrel) for use of a stent or flow diverter, and patients who underwent microsurgical clipping or coiling only and were not on DAPT by way of a backward stepwise multivariate analysis. Results: 443 patients were admitted for management...