Abstract TP144: Preclinical Translation and Validation of C3a Receptor Antagonist in Thromboembolic Stroke

Saif Ahmad,Rafay Chaudhary,Adam Kindelin,Chirayu Pandya,Nasrul Hoda,Andrew F. Ducruet

Abstract TP144: Preclinical Translation and Validation of C3a Receptor Antagonist in Thromboembolic Stroke

2019

Saif Ahmad
Rafay Chaudhary
Adam Kindelin
Chirayu Pandya
Nasrul Hoda
Andrew F. Ducruet

Background: Activation of complement component C3 and expression of cerebro-endothelial C3a receptor (C3aR) occur after stroke regardless of the dynamics of cerebral blood flow (CBF) changes. Moreo...

Keywords:

Antagonist
Physical therapy
Oncology
Thromboembolic stroke
Diabetes mellitus
C3a receptor
Medicine
Internal medicine
Stroke
Cerebral blood flow
Cardiology
Thrombolysis
Inflammation

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