COMPOUND SCN5A MUTATION AND FGF12 VARIATION CAUSE BRUGADA SYNDROME

Background: Mutations in the voltage-gated sodium channel (SCN5A; Nav1.5) and its regulating genes, such as fibroblast growth factor 12 (FGF12), are linked to Brugada syndrome (BrS). The goal of this study is to identify additional FGF12 mutations and variants that may be linked to BrS. Methods: