Clinical significance of C-reactive protein and prealbumin detection during the acute exacerbation of COPD

Objective To discuss the clinical significance of C-reactive protein and prealbumin detection during the acute exacerbation of COPD.Methods The leves of CRP and prealbumin in fifty-six patients at the acute exacerbation of COPD before and after treatment were detected.At the same time,fifty-four normal healthy volunteers were choosed as normal control group,and the results were compared and analyzed between the two groups.Results In acute stage of COPD,the patients plasma CRP level increased distinctly,after given therapies,and the plasma CRP level decreased,with a significant difference between the groups,(The patients had higher value than controls,P0.05)In acute stage of COPD,the patientsplasma prealbumin level decreased distinctly,after given therapies,and the plasma prealbumin level increased,with a significant difference between the groups,(The patients had lower value than the controls,P0.05).Conclusions Plasma CRP level and prealbumin were sensitive indexes to infection and curative effect judgment.