S-Nitrosylation of Muscle LIM Protein Facilitates Myocardial Hypertrophy Through Toll-Like Receptor 3-Mediated Receptor-Interacting ProteinKinase 3 and NLRP3 Inflammasome Activation

Xin Tang,Lihong Pan,Shuang Zhao,Feiyue Dai,Menglin Chao,Hong Jiang,Xuesong Li,Zhe Lin,Zhengrong Huang,Guoliang Meng,Chun Wang,Chan Chen,Jin Liu,Xin Wang,Albert Ferro,Hong Wang,Hongshan Chen,Yuanqing Gao,Qiulun Lu,Liping Xie,Yi Han,Yong Ji

S-Nitrosylation of Muscle LIM Protein Facilitates Myocardial Hypertrophy Through Toll-Like Receptor 3-Mediated Receptor-Interacting ProteinKinase 3 and NLRP3 Inflammasome Activation

2020

Background: S-nitrosylation (SNO), a prototypic redox-based posttranslational modification, is involved in the pathogenesis of cardiovascular disease. The aim of this study was to determine the rol...

Keywords:

Toll-like receptor
NLRP3 inflammasome activation
Cell biology
Pathogenesis
Internal medicine
Diabetes mellitus
Muscle hypertrophy
Medicine
S-Nitrosylation
Muscle LIM protein
Receptor
Cardiology
Kinase
TLR3
Inflammasome
Pyrin domain
NOD-like receptor

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